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Creators/Authors contains: "Wilson, William"

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  1. Abstract The significance of large tropical lakes as environmental reservoirs of Vibrio cholerae in cholera endemic countries has yet to be established. By combining large scale plankton sampling, microbial culture and ultrasensitive molecular methods, namely Droplet Digital PCR (ddPCR) and targeted genomics, the presence of Vibrio cholerae was investigated in a 96,600 L volume of surface water collected on a 322 nautical mile (596 km) transect in Lake Tanganyika. V. cholerae was detected and identified in a large area of the lake. In contrast, toxigenic strains of V. cholerae O1 or O139 were not detected in plankton samples possibly in relation to environmental conditions of the lake ecosystem, namely very low salinity compared to marine brackish and coastal environments. This represents to our knowledge, the largest environmental study to determine the role of tropical lakes as a reservoir of V. cholerae . 
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  2. Caching techniques are widely used in today’s computing infrastructure from virtual memory management to server cache and memory cache. This paper builds on two observa- tions. First, the space utilization in cache can be improved by varying the cache size based on dynamic application demand. Second, it is easier to predict application behavior statistically than precisely. This paper presents a new variable-size cache that uses statistical knowledge of program behavior to maximize the cache performance. We measure performance using data access traces from real-world workloads, including Memcached traces from Facebook and storage traces from Microsoft Research. In an offline setting, the new cache is demonstrated to outperform even OPT, the optimal fixed- size cache which makes use of precise knowledge of program behavior. 
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